Tert-Butyldimethylsilyl Chloride Cas:18162-48-6

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Product Description:

Product Name: tert-Butyldimethylsilyl chloride CAS NO: 18162-48-6

 

Synonyms:

Silane, chloro(1,1-dimethylethyl)dimethyl-;

tert-Butyl(chloro)dimethylsilane,tert-Butyldimethylchlorosilane,TBDMSCl;

tert-Butyl(chloro)dimethylsilane;

 

Chemical & Physical Properties:

Appearance: White solid

Assay :≥99.00%

Density: 0.81

Boiling Point: 125℃

Melting Point: 85-91℃

Flash Point: 22℃

Refractive Index: n20/D 1.46

Stability: Stable under normal temperatures and pressures.

Storage Condition: Store at 5℃

Vapor Pressure: 12.089mmHg at 25℃

Water Solubility: Soluble in chloroform and ethyl acetate. Insoluble in water.

Sensitive: Moisture Sensitive

 

Safety Information:

RTECS: VV2000000

Hazard Class: 4.1

Safety Statements: S16-S25-S36/37/39-S45

HS Code: 29310095

WGK Germany: 2

Packing Group: III

RIDADR: UN 2925 4.1/PG 2

Risk Statements: R10; R34

Hazard Code: C

Symbols: GHS02, GHS05

Signal Word: Danger

Hazard Declaration: H228; H314

Caution Statements: P210; P280; P305 + P351 + P338; P310

 

Used for the synthesis of prostaglandins, some antibiotics, lipid-lowering drugs lovastatin and simvastatin auxiliary raw materials. Used as pharmaceutical intermediates and in organic synthesis, as a hydroxyl protectant in organic synthesis. It is used for the synthesis of drug intermediates and organic compounds. It is a kind of steric blocking organosilicon protectant, which is widely used in the synthesis of active drugs. It is used in the synthesis of ribonucleoside as a protective group of hydroxyl groups, as an oxidant, and as a decyanogen. Silanylating agent. As hydroxyl protectant in organic synthesis, derivatization reagents are used for analysis and preparation. Protective tertiary alcohols. Reaction with alcohols to form a silica ether. Determination of conformation Chemicalbook of cholesterol derivatives. Synthetic prostaglandins, the adjunct raw materials of some antibiotics and the lipid-lowering drugs Lovastatin and Simvastatin.

 

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