Rivastigmine Tartrate Cas:129101-54-8

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Product Description:

Product Name: Rivastigmine tartrate CAS NO: 129101-54-8

 

Synonyms:             

N-Ethyl-N-methylcarbamic Acid 3-[(S)-1-(Dimethylamino)ethyl]phenyl Ester L-Tartrate;

Rivastigmine;

(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate;

 

Chemical & Physical Properties:

Appearance: White to Off-White Powder

Assay :≥99.0%

Boiling Point: 316.2℃ at 760 mmHg

Melting Point: 123-125℃

Flash Point: 145℃

Vapor Pressure: 0.000416mmHg at 25℃

Storage temp.: 2-8℃

Solubility: H2O: soluble15mg/mL, clear

 

Safety Information:

Safety Statements: S24/25

HS Code: 2942000000

Hazard Code: Xi

Hazard Class: 6.1

Packing Group: III

 

Rivastigmine tartrate, an cholinesterase inhibitor(IC50= 5.5 uM), inhibits both butyrylcholinesterase and acetylcholinesteraseIC50 value: 5.5 uMTarget: AChERivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer”s type and dementia due to Parkinson”s disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions. Rivastigmine, a cholinesterase inhibitor, inhibits both butyrylcholinesterase and acetylcholinesterase. It is thought to work by inhibiting these cholinesterase enzymes, which would otherwise break down the brain chemical acetylcholine.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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