Mildronate Dehydrate Cas:86426-17-7

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Product Description:

Product Name: Mildronate dehydrate CAS NO: 86426-17-7

 

Synonyms:

3-(2,2,2-Trimethylhydrazinium)propionate dihydrate;

Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt;

Meldonium;

 

Chemical & Physical Properties:

Appearance: White to off-white powder

Assay :≥99.00%

Storage Temp.: 2-8℃

Solubility: H2O: >40mg/mL

 

Safety Information:

Hazard Code: Xi

Risk Statements: R36/37/38

Safety Statement: S26

WGK Germany: 3

Symbol: GHS07

Signal Word: Warning

Hazard Statements: H315-H319-H335

Precautionary Statements: P261-P305 + P351 + P338

 

At present, the commonly used drugs for the prevention and treatment of myocardial ischemia in clinic mainly include nitrate esters, β-blockers, calcium channel blockers and Chinese herbal medicine. Their mechanism of action is to increase the blood supply to the myocardium. Reduce oxygen consumption; Protect ischemic cardiomyocytes from damage to serosal membrane mitochondria and nuclear membrane; Improve myocardial metabolism, increase the supply of nutrient substrates and penetrate into ischemic areas. In recent years, the role of drugs to improve myocardial metabolism in preventing myocardial ischemia-reperfusion Chemicalbook injury has attracted much attention from many scholars. Myocardial metabilityameliorants are drugs that increase myocardial tolerance to ischemia and/or reperfusion injury by improving myocardial metabolism at the myocyte level. Therefore, it has obvious myocardial protective effect, and has no obvious effect on hemodynamic parameters, cardiac blood supply and cardiac oxygen consumption have no significant changes. These drugs are also known as cellular antiischemia agents because of their distinct differences with other antiischemia agents.

 

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