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Product Description:
Product Name: Primaquine diphosphate CAS NO: 63-45-6
Synonyms:
4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine,phosphoric acid;
8-(4-amino-1-methylbutylamino)-6-methoxyquinoline diphosphate salt;
4-pentanediamine, n(sup 4)-(6-methoxy-8-quinolinyl)- phosphate;
Chemical & Physical Properties:
Appearance: Orange powder
Assay :≥99.00%
Boiling Point: 451.1℃ at 760 mmHg
Melting Point: 199-205℃
Flash Point: 226.6℃
Water Solubility: Moderately soluble
Stability: Stable. Incompatible with strong oxidizing agents.
Storage Condition: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Safety Information:
RTECS: VA9660000
Hazard Class: 6.1(b)
Safety Statement: S45
HS Code: 2933499090
WGK Germany: 3
Packing Group: III
RIDADR: UN 2811
Risk Statement: R25
Hazard Code: T
Primaquine diphosphate is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P. ovale infection for its ability to kill late-stage gametocytes and hypnozoites. In historical terms, this aminoquinoline was the stimulus for the discovery of glucose-6-phosphate (G6P) dehydrogenase deficiency as it induced hemolytic anemia in patients lacking the G6P-metabolizing enzyme.
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