Miconazole Nitrate Cas:22832-87-7

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Product Description:

Product Name: Miconazole nitrate CAS NO: 22832-87-7

 

Synonyms:

1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole;

monistat-Derm;

Florid;

 

Chemical & Physical Properties:

Appearance: White crystal powder

Assay :≥99.00%

Density: 1.451g/cm3

Boiling Point: 555.1℃ at 760 mmHg

Melting Point: 170-185℃

Flash Point: 289.5℃

Water Solubility: Slightly soluble in water. Soluble in propylene glycol or pyridine.

 

Safety Information:

RTECS: NI4771000

Hazard Class: 6.1(b)

Safety Statements: S36/37

HS Code: 2933990090

Packing Group: III

WGK Germany: 3

RIDADR: UN 3249

Risk Statements: R22; R43

Hazard Code: Xn

Caution Statement: P280

Hazard Declaration: H302; H317

Symbol: GHS07

Signal Word: Warning

 

1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole is a kind of broad-spectrum anti-fungal drug and can be applied to the treatment of deep fungal infections. Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp. Miconazole Nitrate is an imidazole antifungal agent.Target: AntifungalMiconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process. From Wikipedia.

 

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