Carteolol Hydrochloride Cas:51781-21-6

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Product Description:

Product Name: Carteolol hydrochloride CAS NO: 51781-21-6

 

Synonyms:

5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one,hydrochloride;

Carteolol monohydrochloride;

Carteolol Hydrochloride;

 

Chemical & Physical Properties:

Appearance: Crystalline Solid

Assay :≥99.0%

Density: 1.13g/cm3

Boiling Point: 518.6℃ at 760mmHg

Melting Point: 278℃

Flash Point: 267.4℃

Storage Condition: Refrigerator

 

Safety Information:

RTECS: VC8282000

HS Code: 2933790002

 

β-Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic; antiglaucoma. Carteolol HCl is a non-selective beta blocker used to treat glaucoma.Target: Beta adrenergic ReceptorCarteolol HCl is a beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent. Carteolol hydrochloride at 1 mmol/L (P<0.05) significantly inhibited H2O2-induced cell damage and was able to scavenge O2 (EC50 value: 48 mmol/L). carteolol hydrochloride has a protective action against UVB-induced HCEC damage, and its radical scavenging ability may be an important basis for this effect. The new alginate formulation of long-acting carteolol 1% given once daily is as effective as standard 1% carteolol given twice daily, with no meaningful differences regarding safety. This efficacy wasy was verified at 9 AM (24 hours after the last drop of long-acting carteolol or 12 hours after that of standard carteolol) and at 11 AM (2 hours after the morning drop). The new alginate formulation of long-acting carteolol 1% given once a day is effective and well tolerated by glaucoma patients who require chronic treatment.

 

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