Carfilzomib Cas:868540-17-4

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Product Description:

Product Name: Carfilzomib CAS NO: 868540-17-4

 

Synonyms:

UNII-72X6E3J5AR;

Carfilzomib (PR-171);

PR-171;

 

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.0%

Density: 1.162g/cm3

Boiling Point: 975.627℃ at 760 mmHg

Flash Point: 543.84℃

Refractive Index: 1.551

 

Safety Information:

HS Code: 2933790090

 

Carfilzomib (marketed under the trade name Kyprolis, developed by Onyx Pharmaceuticals) is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.

The U.S. Food and Drug Administration (FDA) approved it on 20 July 2012 for use in patients with multiple myeloma who have received at least two prior therapies, including treatment with bortezomib and an immunomodulatory therapy (such as lenalidomide) and have demonstrated disease progression on or within 60 days of completion of the last therapy. Approval is based on response rate. Clinical benefit, such as improvement in survival or symptoms, has not been verified.

The abbreviation CFZ is common for referring to carfilzomib, but abbreviating drug names is not best practice in medicine.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

 

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