ursodeoxycholic acid Cas:128-13-2

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ursodeoxycholic acid

Synonyms:
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;7β-Hydroxylithocholic acid3α,7β-Dihydroxy-5β-cholan-24-oic acid5β-Cholan-24-oic acid-3α,7β-diol5β-Cholanic Acid-3α,7β-diol3α,7β-Dihydroxy-5β-cholanic AcidUrsodeoxycholic Acid
 
molecular formula: C24H40O4
Molecular weight: 392.57200
 
Physical Properties:
Appearance and properties: white crystalline powder
Density: 1.128 g/cm3
Boiling point: 547.1ºC at 760mmHg
Melting point: 203-206ºC
Flash point: 298.8ºC
Stability: Stable under normal temperatures and pressures.

 
Specification:
Items of Analysis Standard of Analysis Test Results
Appearance White to off-white powder Conform
Assay 99.0%-101.0% 99.9%
Melting point 200-204℃ 201.4-203.5℃
Specific rotation +58.0°~ +62.0° 60.1°
Lithocholic acid ≤0.1% 0.05%
Chenodeoxycholic acid ≤1.0% 0.12%
Other single impurity ≤0.1% 0.06%
Total impurities ≤1.5% 0.62%
Acetone ≤0.5% 0.05%
Ethyl acetate ≤0.5% 0.04%
Isopropyl alcohol ≤0.5% 0.09%
Heavy Metals ≤20 ppm Conform
Conclusion Conform to EP8.0
 
Application:
Ursodiol reduces cholesterol absorption and acts on the dissolution of gallstones.
 
Package and Storage:
Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.
 



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