Chemicals

Trometamol

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Synonyms：

TRIS

Pehanorm

THAM

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

TRISMAT

riladyl

Trizma

thamset

Talatrol

Tham-E

Tromethamine

Molecular Formula: C4H11NO3

Molecular Weight: 121.13500

Appearance and properties: white crystalline powder

Density: 1,353 g/cm3

Boiling point: 219-220 °C10 mm Hg(lit.)

Melting point: 167-172 °C(lit.)

Flash point: 219-220°C/10mm

Refractive index: 1.531

Water solubility: 550 g/L (25 ºC)

Stability: Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.

Storage conditions: 2-8ºC

use:

Pharmaceutical intermediates, biochemical reagents, pharmaceutical raw materials, acid-base balance regulators. For acute respiratory and metabolic acidemia.

Items	Specification	Test Results
Appearance	White crystal powder	Conforms
Assay	≥99.5%	99.96%
Identification	IR	Conforms
Melting point	168-172℃	170.6-171.8℃
Solubility (40% aqueous solution)	Colorless and clear	Conforms
Heavy metal	≤5ppm	Conforms
Moisture	≤0.6%	0.3%
PH (5% aqueous solution)	10.0-11.5	10.68
Fe	≤1ppm	Conforms
SO₄	≤10ppm	Conforms
Cl	≤3ppm	Conforms
Ultraviolet absorbance: 280nm (40% aqueous solution)	≤0.07	0.067
Ultraviolet absorbance: 400nm (40% aqueous solution)	≤0.02	0.009
Conclusion	Conforms to Factory Standard

Trometamol

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