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Chemical Name: trans-1,2-Cyclohexanedicarboxylic acid
trans-Cyclohexane-1,2-dicarboxylic acid,trans-Hexahydrophthalic acid
1,2-Cyclohexanedicarboxylic acid, trans-
Trans-1,2-cyclohexane carboxylic acid
Molecular Formula: C8H12O4
Molecular Weight: 172.17800
Physical and Chemical Properties:
Density: 1.314 g / cm3
Boiling point: 384.1ºC at 760 mmHg
Melting point: 228-230 ° C (lit.)
Flash point: 200.3ºC
Refractive index: 1.521
Appearance: white crystalline powder
Loss on drying: ≤1.0％
Sulphated ash(％): ≤0.1％
Heavy metals(ppm): ≤20
Residue on ignition:≤0.1%
25kg cardboard drum or according to customer specified requirements
Storage:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Application: trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.. Intermediates of Lurasidone hydrochloride CAS:367514-88-3.
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