Torasemide Cas:56211-40-6

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Product Description:

Product Name: Torasemide CAS NO: 56211-40-6

 

Synonyms:

N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide Torasemide;

TorseMide(DeMadex);

TorseMide API;

 

Chemical & Physical Properties:

Appearance: Crystalline solid

Assay :≥99.00%

Density: 1.283 g/cm3

Melting Point: 163-164℃

Refractive Index: 1.594

Storage Condition: Store in original container in a cool dark place.

Water Solubility: Soluble

 

Safety Information:

RTECS: UT7938000

Safety Statements: S26; S37/39

HS Code: 2935009090

Risk Statement: R36

Hazard Code: Xi

 

Torsemide is a pyridine-sulfonyl urea type loop diuretic.Target: OthersTorasemide is a pyridine-sulfonylurea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension. Torsemide significantly reduced total HF readmissions (relative risk [RR]: 0.41, 95% CI: 0.28-0.61, p < 0.0001) and HF readmissions (RR: 0.53, 95% CI: 0.33-0.84, p = 0.008) as well as CV readmissions (RR: 0.77, 95% CI: 0.60-0.98, p = 0.03) in patients with ”at least 1 readmission.” Torsemide caused a 14% reduction in all-cause mortality (RR: 0.86 [0.53-1.39], p = 0.54). Torsemide significantly reduces HF and CV-related hospital readmissions in systolic HF. Furthermore, torsemide is associated with a trend in reducing all-cause mortality . Torsemide has several characteristics that make it suitable for treatment of advanced heart failure including longer half-life, increased potency of diuretic action, and anti-aldosterone effects. This case report details the administration of torsemide in 3 dogs with advanced heart failure and apparent furosemide resistance .

 

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