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Product Description:
Product Name: Tetrahydro-4H-pyran-4-one CAS NO: 29943-42-8
Synonyms:
tetrahydro-4-pyranone;
4-Oxacyclohexanone;
Oxan-4-one;
Chemical & Physical Properties:
Appearance: Colorless to light yellow liquid
Assay :≥99.00%
Density: 1.065 g/cm3
Boiling Point: 166-166.4℃
Flash Point: 56ºC-63.6℃
Refractive Index: 1.451-1.453
Water Solubility: MISCIBLE
Stability: Stable under normal temperatures and pressures.
Storage Condition: Keep Cold
Vapor Pressure: 1.69mmHg at 25℃
Safety Information:
Hazard Class: 3.2
Safety Statements: S24/25
HS Code: 29329995
WGK Germany: 3
Packing Group: III
RIDADR: UN 1224 3/PG 3
Risk Statements: R10; R36/37/38
Hazard Codes: Xi; F
Hazard Note: Keep Cold/Flammable/Irritant
Tetrahydro-4-pyrone is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes.
The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3.
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