We are Tert-butyl N-[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamate CAS:247068-82-2 manufacturer and supplier in China, Pls send inquiry of to info@nbinno.com of visit www.nbinno.com our official website should you have any interests
Product Description:
Product Name:
tert-butyl N-[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamate CAS NO: 247068-82-2
Synonyms:
Boc-leucine-epoxyketone;
Carfilzomib intermediate;
Boc-L-leucine epoxyketone;
Chemical & Physical Properties:
Appearance: White to off-white powder
Assay :≥99.0%
Density: 1.1±0.1 g/cm3
Boiling Point: 369.8±37.0 ℃ at 760 mmHg
Flash Point: 177.5±26.5 ℃
Vapor Pressure: 0.0±0.8 mmHg at 25℃
Index of Refraction: 1.472
PKa: 11.08±0.46 (Predicted)
Safety Information:
Signal Word: Warning
Hazard Statement: H302
Precautionary Statements: P280-P305+P351+P338
PR171 intermediates (BOC protected) can be used as pharmaceutical intermediates. tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
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