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Product Description:
Product Name: terazosin hydrochloride dihydrate CAS NO: 70024-40-7
Synonyms:
4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride;
Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-,hydrochloride, hydrate (1:1:2);
Terazosin Hydrochloride ImpuritV;
Chemical & Physical Properties:
Appearance: White or off-white crystalline powder
Assay :≥98.0%
Boiling Point: 664.5℃ at 760 mmHg
Melting Point: 215 – 217℃
Solubility: Sparingly soluble in water, slightly soluble in methanol, very slightly soluble in ethanol (96 per cent), practically insoluble in acetone.
Safety Information:
Symbol: GHS07
Signal Word: Warning
Risk Statement: S22
RTECS: TK8046000
Hazard Code: Xn
HS Code: 2934990002
Hazard Statement: H302
Precautionary Statements: P301 + P312 + P330
Toxicity: LD50 in male, female rats (mg/kg): 277, 293 i.v. (Fort)
Terazosin Hydrochloride Dihydrate is an α-1-adrenergic blocker related to prazosin. An alpha-1 adrenoceptor selective antagonist. Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR.
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