Simvastatin Cas:79902-63-9

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Product Description:

Product Name: Simvastatin CAS NO: 79902-63-9

 

Synonyms:

(1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste;

7-beta,8-beta(2s*,4s*),8a-beta))-alph;

Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro- 4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha,3-alpha,7- beta,8-beta(2S*,4S*),8a-beta));

 

Chemical & Physical Properties:

Appearance: White to off- white crystalline powder

Assay :≥99.00%

Density: 1.11 g/cm3

Boiling Point: 564.9℃ at 760 mmHg

Melting Point: 139℃

Flash Point: 184.8℃

Refractive Index: 1.53

Storage Condition: 0-6℃

Vapour Pressure: 0.0±3.5 mmHg at 25℃

 

Safety Information:

RTECS: EK7798000

Hazard Class: 9

Safety Statements: S26; S36

Packing Group: III

RIDADR: UN 3077

Risk Statements: R36/37/38

Hazard Code: Xi

 

Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid (fat) levels. It is also used to decrease the risk of heart problems in those at high risk. It is taken by mouth.

Serious side effects may include muscle breakdown, liver problems, and increased blood sugar levels. Common side effects include constipation, headaches, and nausea. A lower dose may be needed in people with kidney problems. There is evidence of harm to unborn babies when taken during pregnancy and it should not be used by those who are breastfeeding. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver.

Simvastatin was developed by Merck and came into medical use in 1992. It is on the World Health Organization”s List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic medication. The wholesale cost in the developing world is 0.01 to 0.12 USD per day as of 2014[update]. In the United States it costs between 0.50 and 1.00 USD per day. Simvastatin is made from the fungus Aspergillus terreus.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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