S-(2-BORONOETHYL)-L-CYSTEINE HYDROCHLORIDE Cas:222638-67-7

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Product Description:

Product Name: S-(2-BORONOETHYL)-L-CYSTEINE HYDROCHLORIDE CAS NO: 222638-67-7

 

Synonyms:

BEC hydrochloride – S-(2-Boronoethyl)-L-cysteine hydrochloride;

(R)-2-amino-3-((2-boronoethyl)thio)propanoic acid hydrochloride;

 

Chemical & Physical Properties:

Appearance: Crystalline solid

Assay :≥98.0%

 

BEC HCl is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM (ph 7.5).target: Arginase II;In vitro: BEC HCl causes significant enhancement of NO-dependent smooth muscle relaxation in this tissue. BEC HCl enhances perivascular and peribronchiolar lung inflammation, mucus metaplasia, NF-κB DNA binding, and mRNA expression of the NF-κB-driven chemokine genes CCL20 and KC, and lead to further increases in airways hyperresponsiveness. In vivo: BEC HCl increased contractility in isolated myocytes from WT and NOS3 but not NOS1 knockout mice.

 

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