Rosuvastatin Calcium

We are Rosuvastatin Calcium CAS:147098-20-2 manufacturer and supplier in China, Pls send inquiry of to info@nbinno.com of visit www.nbinno.com our official website should you have any interests

Synonyms:
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
Rosuvastatin Calcium Salt
Rosuvastatin Hemicalcium
ZD 4522 Calcium Salt
Rosuvastatin Calcium
 
Molecular Formula:  C44H54CaF2N6O12S2
Molecular Weight: 1001.14000

Appearance and properties: white to off-white crystalline solid
Boiling point: 745.6ºC at 760 mmHg
Melting point: 122ºC
Flash point: 404.7ºC

Storage conditions: -20°C Freezer

use:Lipid-lowering drugs.

Items of Analysis Standard of Analysis Test Results
Appearance Off-white to pale yellow powder Off-white powder
Specific rotation(°  +13.0~+18.0 +17.9
Identification IR Consistent with the reference  Consistent with the reference
Calcium salt Positive response Positive response
GC The main peak retention time consistent with the reference The main peak retention time consistent with the reference
Water
(%,w/w)
≤3.0 2.5
Loss on drying
(%,w/w)
≤3.0 1.7
Relative Substance
(%,area,HPLC)
Single impurity ≤0.10 <0.05
Total impurity ≤1.0 <0.05
Diastereomer
(EP Imp.B)
≤0.15 <0.05
 EP Imp.A ≤0.10 Not detected
5-Keto acid
(EP Imp.C)
≤0.10 <0.05
Assay
(%, ESTD, HPLC)
98.0-102.0 99.7
Conclusion Conforms to Factory Standard


 Rosuvastatin Calcium


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