Rebeprazole Sodium Cas:117976-90-6

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Product Description:

Product Name: Rebeprazole sodium CAS NO: 117976-90-6

 

Synonyms:

Rabeprazole Sodium Salt;

sodium,2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide;

2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole,Pariprazole;

 

Chemical & Physical Properties:

Appearance: White or off white crystalline powder

Assay :≥99.00%

Density: 0.45~0.55 g/ml

Boiling Point: 603.9℃ at 760 mmHg

Melting Point: 140-141℃ dec.

Flash Point: 319.1℃

Storage temp.: Hygroscopic, -20℃ Freezer, Under Inert Atmosphere

 

Safety Information:

HS Code: 2933399090

WGK Germany: 3

 

Rabeprazole sodium(LY307640 sodium) is an antiulcer drug in the class of proton pump inhibitors.Target: Proton PumpRabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.

 

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