Pyrimethamine Cas:58-14-0

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Pyrimethamine

Product Description:

Product Name: Pyrimethamine CAS NO: 58-14-0

 

Synonyms:

2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;

[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;

Pyrimethamine,5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine;

 

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.00%

Density: 1.305g/cm3

Boiling Point: 491.5℃ at 760mmHg

Melting Point: 233-234℃

Flash Point: 251℃

Refractive Index: 1.655

Stability: Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents.

Storage Condition: 0-6℃

 

Safety Information:

RTECS: UV8140000

Hazard Class: 6.1(b)

HS Code: 2933990090

WGK Germany: 3

Packing Group: III

RIDADR: UN 3249

Risk Statement: R22

Hazard Code: Xn

Signal Word: Warning

Symbol: GHS07

Hazard Declaration: H302

 

Pyrimethamine (trade name Daraprim) is a medication used for protozoal infections. It is commonly used as an antimalarial drug (for both treatment and prevention of malaria), and to treat Toxoplasma gondii infections, particularly when combined with the sulfonamide antibiotic sulfadiazine when treating HIV-positive individuals. It works by inhibiting folic acid metabolism via dihydrofolate reductase.

It is on the World Health Organization”s List of Essential Medicines, the most important medications needed in a basic health system.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.



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