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Product Description:
Product Name: PYRIDOSTIGMINE BROMIDE CAS NO: 101-26-8
Synonyms:
3-((Dimethylcarbamoyl)oxy)-1-methylpyridin-1-ium bromide;
mestinonebromide;
PyridostigMine BroMide;
Chemical & Physical Properties:
Appearance: Pale yellow to colorless liquid or white solid
Assay :≥99.0%
Density: 0.9613 g/cm3 (20℃)
Boiling Point: 88 (25 torr)
Melting Point: 154℃
Refractive Index: 1.48 (20℃)
Stability: Stable at normal temperatures and pressures in in a tightly sealed container.
Storage Condition: Keep in a cool, dry location in a tightly closed container when not in use.
Safety Information:
RTECS: UU5270000
Safety Statements: S22; S36/37/39; S45
RIDADR: UN 2811 6.1/PG 2
Risk Statements: R26/27/28
WGK Germany: 3
Hazard Codes: T+
Hazard Class: 6.1
Packing Group: II
Cholinergic, used in the treatment of myasthenia gravis, and is a pre-exposure antidote to chemical warfare agents. Pyridostigmine bromide,3-hydroxy-1-methylpyridinium bromide dimethylcarbamateor pyridostigmine bromide (Mestinon), occurs as a white, hygroscopic,crystalline powder with an agreeable, characteristicodor. It is freely soluble in water, alcohol, and chloroform.
Pyridostigmine bromide is about one fifth as toxic asneostigmine. It appears to function in a manner similar tothat of neostigmine and is the most widely used anticholinesteraseagent for treating myasthenia gravis. Theliver enzymes and plasma cholinesterase metabolize thedrug. The principal metabolite is 3-hydroxy-N-methylpyridinium.Orally administered pyridostigmine has a half-lifeof 90 minutes and a duration of action of between 3 and6 hours.
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