Plitidepsin Cas:137219-37-5

We are Plitidepsin CAS:137219-37-5 manufacturer and supplier in China, Pls send inquiry of to info@nbinno.com of visit www.nbinno.com our official website should you have any interests

Product Description:

Product Name: Plitidepsin CAS NO: 137219-37-5

 

Synonyms:

(2S)-N-[(2R)-1-[[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxopentan-2-yl]-N-methyl-1-(2-oxopropanoyl)pyrrolidine-2-carboxamide;Plitidepsin;

2-9-Didemnin B, 2-(1-(1,2-dioxopropyl)-L-proline)-;

 

Chemical & Physical Properties:

Appearance: Solid

Assay :≥99.0%

Density: 1.24g/cm3

Refractive Index: 1.567

 

Plitidepsin (also known as dehydrodidemnin B, marketed by PharmaMar, S.A. under the trade name Aplidin) is a chemical compound extracted from the ascidian Aplidium albicans. It is currently undergoing clinical trial testing. It is a member of the class of compounds known as didemnins. Plitidepsin is a cyclic depsipeptide that was first isolated from a Mediterranean marine tunicate (Aplidium albicans) and, at present, is manufactured by total synthesis and commercialized as Aplidin?. Its antitumor activity, observed in preclinical in vitro and in vivo studies has prompted numerous clinical trials to be conducted over the last 17 years, alone or in combination with other anticancer agents.

 

If you are interested in our products or have any questions, please feel free to contact us!

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

Related Products:[2-(phosphanylidenemethyl)phenyl]methylidenephosphane manufacturer | Isophthalsaeure-bis-(α-methyl-hydrazid) supplier | 4-(4-methoxybenzoyl)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one producer.