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Product Description:
Product Name: Plecanatide CAS NO: 467426-54-6
Synonyms:
105: PN: WO2012037380 SEQID: 105 claimed protein;
1: PN: WO2008151257 SEQID: 1 claimed protein;
20: PN: WO02078683 SEQID: 20 claimed protein;
Chemical & Physical Properties:
Appearance: Powder or liquid
Assay :≥99.00%
Density: 1.47±0.1 g/cm3(Predicted)
Boiling Point: 2120.0±65.0℃(Predicted)
Flash Point: 1235.9±34.3℃
Vapour Pressure: 0.0±0.6 mmHg at 25℃
Index of Refraction: 1.631
Plecanatide, an analogue of uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis.
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