Olaparib Cas:763113-22-0

We are Olaparib CAS:763113-22-0 manufacturer and supplier in China, Pls send inquiry of to info@nbinno.com of visit www.nbinno.com our official website should you have any interests

Product Description

Product Name: Olaparib CAS NO:763113-22-0

 

Synonyms:

1(2H)-Phthalazinone, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-;

1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine;

AZD-2281; AZD2281;

azd2281 Olaparib;

4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}-4-fluorobenzyl)-1(2H)-phthalazinone;

Olaparib; Lynparza;

4-(3-{[4-(Cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one;

 

Chemical & Physical Properties

Appearance :white Solid.

Assay : ≥99.5%

Density:1.43 g/cm3

 

Olaparib (AZD-2281, trade name Lynparza) is an FDA-approved targeted therapy for cancer, developed by KuDOS Pharmaceuticals and later by AstraZeneca. It is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair. It acts against cancers in people with hereditary BRCA1 or BRCA2 mutations, which include some ovarian, breast, and prostate cancers. In December 2014, olaparib was approved for use as a single agent by the EMA and the FDA. The FDA approval is in for germline BRCA mutated (gBRCAm) advanced ovarian cancer that has received three or more prior lines of chemotherapy.

 

If you are interested in our products or have any questions, please feel free to contact us!

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

Related Products:8-chloro-2,3-dihydro[1,4]dioxino[2,3-f]quinoline-9-carbaldehyde manufacturer | Octanamide, 2-[(R)-[4-(2-butynyloxy)phenyl]sulfinyl]-N-hydroxy-, (2S)- supplier | rel-(((3R,4S)-heptan-4-yl-3-d)oxy)benzene producer.