Norethindrone Cas:68-22-4

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Norethindrone

Product Description:

Product Name: Norethindrone CAS NO: 68-22-4

 

Synonyms:             

17ALPHA-ETHYNYL-17BETA-HYDROXY-19-NOR-4-ANDROSTEN-3-ONE;

19-NOR-4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;

19-NORETHINDRONE;

 

Chemical & Physical Properties:

Appearance: Off-White to Pale Yellow Solid

Assay :≥99.0%

Density: 1.15 g/cm3

Boiling Point: 447℃ at 760 mmHg

Melting Point: 205-206℃

Refractive Index: 1.577

Storage Condition: -20℃ Freezer

 

Safety Information:

RTECS: RC8975000

Safety Statements: S22; S36/37/39; S45; S26

HS Code: 2937290090

WGK Germany: 3

Risk Statement: R40

Hazard Code: Xn

Hazard Declaration: H351

Signal Word: Warning

Symbol: GHS08

 

Norethisterone (INN, BAN), also known as norethindrone (USAN), as well as 19-nor-17α-ethynyltestosterone, but more commonly known under its trade name Utovlan®, is a steroidal progestin used in some combined oral contraceptive pills and progestogen-only pills, and also available as a standalone drug. It can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with estrogen), or to postpone a period. It is also commonly used to help prevent uterine hemorrhage in complicated non-surgical or pre-surgical gynecologic cases and in treating non responsive cyclical mastalgia. Norethisterone was the first orally highly active progestin to be synthesized.

It was synthesized for the first time by chemists Luis Miramontes, Carl Djerassi, and George Rosenkranz at Syntex in Mexico City in 1951. It was the progestin used in one of the first three oral contraceptives. Its related ester, norethisterone acetate, is used for the same indications. Norethisterone was first introduced, as Norlutin, in 1957.

 

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