Neratinib Cas:698387-09-6

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Product Description:

Product Name: neratinib CAS NO: 698387-09-6

 

Synonyms:

S2150_Selleck;

Neratinib(HKI-272);

HKI 272;

 

Chemical & Physical Properties:

Appearance: White to off-white solid powder

Assay: ≥99.0%

Density: 1.337 g/cm3

Boiling Point: 756.97℃ at 760 mmHg

Flash Point: 411.601℃

 

Safety Information:

HS Code: 29334900

 

Neratinib developed by US Wyeth company is an irreversible epidermal growth factor receptor(EGFR) inhibitor. It is a multiple target point of small molecule tyrosine kinase inhibitors to HER 2 and HER1 after Lapatinib, and is an irreversible ErbB receptor tyrosine kinase inhibitor. Neratinib could selectively inhibit HER-1 and HER-2 of EGFR family(IC50 was 92 nmol/L and 59 nmol/L, respectively).

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

 

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