MonoMethylauristatin F(MMAF) Cas:745017-94-1

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MonoMethylauristatin F(MMAF)

Product Description:

Product Name: MonoMethylauristatin F(MMAF) CAS NO: 745017-94-1

 

Synonyms:

(2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;

Monomethyl auristatin phenylalanine;

Monomethylauristatin F;

 

Chemical & Physical Properties:

Appearance: Solid powder

Assay :≥99.0%

Density: 1.116±0.06 g/cm3 (20℃ 760 mmHg), Calc.

Water Solubility: Slightly soluble (2.8 g/L) (25℃), Calc.

Boiling Point: 896.8±65.0 ℃(Predicted)

Storage temp.: Sealed in dry,Room Temperature

Vapour Pressure: 0.0±0.3 mmHg at 25℃

Index of Refraction: 1.522

 

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.



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