Metronidazole Cas:443-48-1

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Product Description:

Product Name: Metronidazole CAS NO: 443-48-1

 

Synonyms:

1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;

2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol;

2-methyl-5-nitroimidazole-1-ethanol;

 

Chemical & Physical Properties:

Appearance: White to slightly yellow crystalline powder

Assay :≥99%

Density: 1.45 g/cm3

Boiling Point: 405.4℃　at 760 mmHg

Melting Point: 159-163℃

Flash Point: 199℃

Refractive Index: 1.612

Stability: Stable. Incompatible with strong oxidizing agents.

Storage Condition: 2-8℃

Vapor Pressure: 2.67E-07mmHg at 25℃

Water Solubility: <0.1 g/100 mL at 20℃

 

Safety Information:

Symbol: GHS08

Signal Word: Warning

Hazard Code: T

HS Code: 2933990090

WGK Germany: 3

Caution Statement: P281

Hazard Declaration: H351

RTECS: XH8425000

Risk Statements: R40; R46; R45

Safety Statements: S36/37-S45-S53

 

Metronidazole (MNZ), marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. It is the drug of choice for a first episode of mild-to-moderate Clostridium difficile colitis. Metronidazole is available by mouth, as a cream, and intravenously.

Common side effects include nausea, a metallic taste, loss of appetite, and headaches. Occasionally seizures or allergies to the medication may occur. Metronidazole should not be used in early pregnancy but appears to be safe later in pregnancy. It should not be used when breastfeeding.

Metronidazole began to be commercially used in 1960 in France. It is on the World Health Organization”s List of Essential Medicines, the most important medications needed in a basic health system. It is available in most areas of the world. The pills are not very expensive being between 0.01 and 0.10 USD each. In the United States it is about 26 USD for ten days of treatment.

 

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