Methyldopa Cas:555-30-6

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Product Description:

Product Name: Methyldopa CAS NO: 555-30-6

 

Synonyms:

Methyldopa Sesquihydrate;

Alpha-methyl-L-dopa;

L-Tyrosine, 3-hydroxy-α-methyl-;

 

Chemical & Physical Properties:

Appearance: Colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form.

Assay :≥98.0%

Density: 1.403g/cm3

Boiling Point: 441.6℃ at 760mmHg

Melting Point: 300℃

Flash Point: 220.9℃

Refractive Index: -14 ° (C=1, H2O)

Water Solubility: Soluble

Soluble: Soluble in DMSO (75 mM), water, and dilute hydrochloric acid.

Stability: Stable under normal temperatures and pressures.

Storage Condition: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

 

Safety Information:

RTECS: YP2860000

Safety Statements: S24/25

HS Code: 2918199090

WGK Germany: 3

 

Methyldopa (L-α-Methyl-3,4-dihydroxyphenylalanine; Aldomet, Aldoril, Dopamet, Dopegyt, etc.) is a centrally acting antihypertensive agent. It is metabolized to alpha-methylnorepinephrine in the brain, and this compound is thought to activate central alpha-2 adrenergic receptors (Gerber, 1990). Being a selective agonist for α2 adrenergic receptors, psychoactive drug is used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (previously known as pregnancy-induced hypertension (PIH)).

It is on the World Health Organization”s List of Essential Medicines, a list of the most important medication needed in a basic health system.

 

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