Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Cas:1235865-75-4

We are Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate CAS:1235865-75-4 manufacturer and supplier in China, Pls send inquiry of to info@nbinno.com of visit www.nbinno.com our official website should you have any interests

Product Description:

Product Name: Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate CAS NO: 1235865-75-4

 

Synonyms:

methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate;

ABT199 intermediate 3;ABT199 intermediates;

ABT-199 Intermediate;

 

Chemical & Physical Properties:

Appearance: White to off-white powder

Assay :≥99.00%

Density: 1.377±0.06 g/cm3(Predicted)

Pka: 13.21±0.40(Predicted)

Boiling Point:444.0±45.0℃ at 760 mmHg

Flash Point: 222.3±28.7℃

Vapor Pressure: 0.0±1.1 mmHg at 25℃

Index of Refraction: 1.640

 

Safety Information:

Signal Word: Warning     

Precautionary Statements: P261-P305+P351+P338

Hazard Statements: H302-H315-H319-H335

 

Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate is an intermediate of ABT 199, a potent and selective Bcl-2 inhibitor with strong antitumor activity while preserving platelets. Its practical use is in the treatment of chronic lymphocytic leukemia cells and estrogen receptor positive breast cancer.

 

If you are interested in our products or have any questions, please feel free to contact us!

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

Related Products:3-(chloromethyl)-5-phenyl-1H-pyrazole hydrochloride manufacturer | 2-Methyl-ceramidonin-carbonsaeure-(8) supplier | (2R,3R,4R)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-[1-(dimethoxy-phosphoryl)-meth-(E)-ylidene]-pyrrolidine-1-carboxylic acid benzyl ester producer.