methoxsalen

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Synonyms:
9-methoxypsoralen
7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-
Methoxsalen
8-MP
8-Methoxypsoralen
Puvamet
Uvadex
8-MOP,9-Methoxyfuro[3,2-g][1]benzopyran-7-one,Ammoidin
Vitpso
Puvalen
Dermox
Xanthotoxin
8-MOP,8-Methoxypsoralen,9-Methoxyfuro[3,2-g][1]benzopyran-7-one
Ammodin
8-methoxypsoralene
9-Methoxy-7H-furo[3,2-g]chromen-7-one
8-MOP
Meloxine
Metoxin
 
Molecular Formula: C12H8O4
Molecular weight:216.19000

Appearance and properties: odorless white to creamy crystalline solid, bitter taste
Density: 1.368g/cm3
Boiling point: 414.8ºC at 760mmHg
Melting point: 148-150 °C(lit.)
Flash point: 204.7ºC
Refractive index: 1.635
Water solubility: PRACTICALLY INSOLUBLE
 
Stability: Stable under normal temperatures and pressures. May decompose when exposed to light.
Storage conditions: Corrosives area. Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Applications: Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound that can be used for psoralen, for the treatment of psoriasis, eczema, vitiligo and some skin lymphomas exposed to the sun. It is a P450 inhibitor.

Items of Analysis Standard of Analysis Test Results
Appearance White crystalline powder White crystalline powder
Identification IR Complies with Std
Heavy Metals ≤ 20ppm ﹤20 ppm
Melting Range  143℃-148℃ 146℃
Water ≤ 0.5% 0.22%
Residue on ignition ≤ 0.1% 0.020%
Impurity(TLC) ≤ 1% Complies with USP
Assay (HPLC) 98-102%  99.94%
Residual solvent Hexane ≤ 290ppm
Toluene ≤ 890ppm
Methano ≤ 3000ppm
Not Detected
Not Detected
Not Detected
Conclusion Conforms to Factory Standard


methoxsalen


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