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Product Description:
Product Name: lenvatinib CAS NO: 417716-92-8
Synonyms:
E7080,E 7080;
Lenvatinib (E7080);
4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide;
Chemical & Physical Properties:
Appearance: White to off-white solid powder
Assay: ≥98.0%
Density: 1.469g/cm3
Boiling Point: 627.242℃ at 760 mmHg
Flash Point: 333.144℃
Refractive Index: 1.697
Solubility: Soluble in DMSO
Storage condition: Short term storage (weeks): 0 – 4℃ under dry condition; Long term storage (months): -20 ℃under dry condition
Safety Information:
Hazard Statements: Causes serious eye irritation. Suspected of damaging fertility or the unborn child
Precautionary Statements General: Keep out of reach of children.
Lenvatinib (trade name Lenvima) is an anti-cancer drug for the treatment of certain kinds of thyroid cancer, and potentially for other cancers as well. It was developed by Eisai Co. and acts as a multiple kinase inhibitor against the VEGFR1, VEGFR2 and VEGFR3 kinases. E7080 (Lenvatinib) is a multi-target inhibitor of VEGFR2 and VEGFR3 with IC50 of 4 nM and 5.2 nM, respectively.
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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
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