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Product Description:
Product Name: HBTU CAS NO: 94790-37-1
Synonyms:
O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Hexafluorophosphate;
[benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate;
Chemical & Physical Properties:
Appearance: white crystalline powder
Assay :≥99.0%
Flash Point:200℃
Melting point:200℃
Water Solubility:acetonitrile: 0.1 g/mL, clear
HBTU (2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate) is a coupling reagent used in solid phase peptide synthesis. It was introduced in 1978 and shows resistance against racemization. It is used because of its mild activating properties.
HBTU is a coupling agent for peptide synthesis. The main advantages are: very low racemization, simple reaction conditions, short reaction time, and high yield; the latest research shows that the crystal and solution structure of the coupling agent is guanidine salt N -Oxides, not urea cationic compounds.
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