FGF-401 Cas:1708971-55-4

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Product Description:

Product Name: FGF-401 CAS NO: 1708971-55-4

 

Synonyms:

N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide;

FGF-401;

8-naphthyridine-1(2H)-carboxamide;

 

Chemical & Physical Properties:

Appearance: Solid or powder

Assay :≥99.0%

Boiling Point: 852.1±65.0℃(Predicted)

Density: 1.39±0.1 g/cm3 (Predicted)

PKa: 11.40±0.20 (Predicted)

Flash Point: 469.1±34.3℃

Vapor Pressure: 0.0±3.2 mmHg at 25℃

Index of Refraction: 1.654

 

8- diazonaphthalene -1(2H)- formamide is an organic synthesis intermediate and pharmaceutical intermediate, can be used in the laboratory research and development process and chemical production process. FGF401 is a selective inhibitor of FGFR4 with an IC50 of 1.1 nM. It is reversible and covalently bound to the FGFR4 kinase domain and is at least 1000 times more selective to FGFR4 than to the 65 kinases examined.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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