Ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate Cas:103877-51-6

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Product Description:

Product Name: ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate CAS NO: 103877-51-6

 

Synonyms:

7-Chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester;7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester;

 

Chemical & Physical Properties:

Appearance: Powder

Assay :≥99.00%

Boiling Point: 448.7±45.0℃(Predicted)

Density   1.362±0.06 g/cm3(Predicted)

PKa: -3.24±0.40(Predicted)

Flash Point: 225.2±28.7℃

Vapor Pressure: 0.0±1.1 mmHg at 25℃

Index of Refraction: 1.621

Water Solubility: Insoluble (2.8E-3 g/L) (25℃)

 

Ozenoxacin is a novel non-fluoroquinolone antimicrobial for the treatment of pustular dermatitis and other skin infections by inhibiting DNA rotase and topoisomerase IV as a cream (10g, 1%) for the treatment of bacterial skin infections, including Gram-positive skin and soft tissue infections. The compound has been successfully completed in Phase III clinical trials for the treatment of adult Chemicalbook and children”s pustular dermatitis, showing stronger antimicrobial activity, good safety and tolerability.

 

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