Eplerenone Cas:107724-20-9

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Product Description:

Product Name: Eplerenone CAS NO: 107724-20-9

 

Synonyms:

9,11α-Epoxy-17-hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic Acid γ-Lactone Methyl Ester;

EplerenoneC24H3006;

(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester;Eplerenone for system suitability;

 

Chemical & Physical Properties:

Appearance: White Solid

Assay :≥99.0%

Density: 1.31g/cm3

Boiling Point: 597.9℃ at 760mmHg

Melting Point: 241-243℃

Flash Point: 259.5℃

Refractive Index: 1.587

Vapor Pressure: 0mmHg at 25℃

 

Safety Information:

RIDADR: 3077

WGK Germany: 3

HS Code: 29322090

 

Eplerenone (INN) is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone, though it is much more selective for the mineralocorticoid receptor in comparison (i.e., does not possess any antiandrogen, progestogen, glucocorticoid, or estrogenic effects), and is specifically marketed for reducing cardiovascular risk in patients following myocardial infarction. By modifying the alternative drug Spironolactone, the new drug was developed in part to avoid undesired androgenic side effects in male patients. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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