Dasatinib Monohydrate Cas:863127-77-9

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Product Description:

Product Name: Dasatinib monohydrate CAS NO: 863127-77-9

 

Synonyms:

N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-1,3-thiazole-5-carboxamide monohydrate;

N-(2-chloro-6-methylphenyl)-2-(6-(4-(3-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino) thiazole-5-carboxamide monohydrate;

Dasatinibmonohydrate;

 

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.00%

Density: 1.408 g/cm3

Melting Point: 97-99℃(lit.)

 

Safety Information:

RTECS: QD8530000

Hazard Class: 4.3

Safety Statements: S26; S27; S28

WGK Germany: 3

Packing Group: II

RIDADR: UN 3263 8/PG 2

Risk Statements: R34; R36/37/38

Hazard Codes: C; Xi

 

Dasatinib, also known as Dasa Tin IB, is a grayish to yellow solid chemical. Dasatinib is an antitumor agent that is mainly used in the clinical treatment of adult patients with chronic, accelerated and acute (acute and eluresis) chronic myeloid leukemia (CML) who are resistant to Chemicalbook or intolerant to imatinib mesylate. Dasatinib is used in adult patients who have been treated with Imatinibmesylate/Gleevec and who are resistant or intolerant to all stages of chronic myeloid leukemia (chronic phase, accelerated phase, eluvialicalbook cell shock phase and myeloid cell shock phase). The FDA also approved dasatinib under normal procedures for the treatment of Philadelphia chromosomal positive adults with acute lymphoblastic leukemia who are resistant or intolerant to other therapies.

 

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