Chlorpheniramine Maleate Cas:113-92-8

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Product Description:

Product Name: Chlorpheniramine maleate CAS NO: 113-92-8

 

Synonyms:             

2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (Z)-2-butenedioate (1:1);

dexchlorpheniramine maleate;

2-Pyridinepropanamine;

 

Chemical & Physical Properties:

Appearance: Odorless white crystalline solid or white powder with a bitter taste.

Assay :≥99.0%

Density: 1.107 g/cm3

Boiling Point: 379℃ at 760 mmHg

Melting Point: 130-135℃

Flash Point: 183℃

Storage Condition: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Vapor Pressure: 2.9E-14mmHg at 25℃

 

Safety Information:

RTECS: US6504000

Hazard Class: 6.1(b)

Safety Statements: S36/37/39-S45

HS Code: 2933399090

WGK Germany: 3

Packing Group: III

RIDADR: UN 2811

Risk Statement: R25

Hazard Code: T

 

Chlorphenamine (INN), also called chlorpheniramine (USAN and former BAN), commonly marketed in the form of chlorphenamine maleate, is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice. Although not generally approved as an antidepressant or anti-anxiety medication, chlorphenamine appears to have these properties as well.

Chlorphenamine is part of a series of antihistamines including pheniramine (Naphcon) and its halogenated derivatives and others including fluorpheniramine, dexchlorpheniramine (Polaramine), brompheniramine (Dimetapp), dexbrompheniramine (Drixoral), deschlorpheniramine, triprolidine (Actifed), and iodopheniramine.

The halogenated alkylamine antihistamines all exhibit optical isomerism, and chlorphenamine in the indicated products is racemic chlorphenamine maleate, whereas dexchlorpheniramine is the dextrorotary stereoisomer.

 

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