Catharanthine Cas:2468-21-5

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Product Description:

Product Name: Catharanthine CAS NO: 2468-21-5

 

Synonyms:

(2α,5β,6α,18β)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester;

CatharanthineSulfateBase;

Catharanthine Sulphate;

 

Chemical & Physical Properties:

Appearance: White powder

Assay :≥98.00%

Density: 1.27 g/cm3

Boiling Point: 491.5℃ at 760 mmHg

Melting Point: 138-140℃

Flash Point: 251.1℃

Refractive Index: 1.663

Vapor Pressure: 8.33E-10mmHg at 25℃

Solubility: DMSO: soluble5mg/mL (clear solution; warmed)

 

Safety Information:

WGK Germany: 3

 

Catharanthine is an indole alkaloid analog and an inhibitor of TRPM8. Vincristine is one of the alkaloids of vincristine. Animal experiments show that it has antihypertensive effect, and it is one of the important starting materials for the synthesis of antitumor drugs such as vinorelbine tartrate, vincristine sulfate and vincristine, which are widely used in clinic, and has a wide application value. It inhibits spindle formation, ribonucleic acid and fat synthesis. Vincblastine sulfate can be used in the treatment of Hodgkin”s disease and villous adenoepithelial carcinoma with good efficacy. It also has certain efficacy in lymphatic carcinoma, acute leukemia, breast cancer, ovarian cancer, testicular cancer, etc.

 

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