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Product Description:
Product Name: BI-847325 CAS NO: 1207293-36-4
Synonyms:
3-[3-[[[4-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-2-propynamide;
Chemical & Physical Properties:
Appearance: Crystalline solid
Assay :≥98.0%
Density: 1.3±0.1 g/cm3
Index of Refraction: 1.673
Storage: 3 years -20℃ powder; 6 months -80℃ in solvent.
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.
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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
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