Bardoxolone Methyl Cas:218600-53-4

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Product Description:

Product Name: Bardoxolone methyl CAS NO: 218600-53-4

 

Synonyms:

2-cyano-3,12-dioxoolean-1,9(11)-dien-28-oic acid methyl ester;

2-Cyano-3-(2-thienyl)thioacrylamide;

Bardoxolone (methyl);

 

Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.0%

Density: 1.15g/cm3

Boiling Point: 600.8℃ at 760mmHg

Flash Point: 256.5℃

Refractive Index: 1.558

Vapor Pressure: 2.15E-14mmHg at 25℃

 

Safety Information: HS Code: 2926909090

 

CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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