Chemicals

azelastine hydrochloride Cas:79307-93-0

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Synonyms：

azelastine hydrochloride

1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, hydrochloride (1:1)

4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloride

4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)phthalazin-1(2H)-one hydrochloride

1(2H)-phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride

4-(4-Chlorobenzyl)-2-(1-methyl-4-azepanyl)-1(2H)-phthalazinone hydrochloride (1:1)

4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride

azelastinum [INN_la]

4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride (1:1)

4-(4-Chlorbenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-onhydrochlorid

4-(4-chlorobenzyl)-2-(1-méthylazépan-4-yl)phtalazin-1(2H)-one chlorhydrate

Azelastine (hydrochloride)

molecular formula: C22H25Cl2N3O

Molecular weight: 418.35900

Physical Properties:

Appearance and properties: white crystalline powder

Density: 1.25 g/cm3

Boiling point: 533.9ºC at 760mmHg

Melting point: 225-229ºC

Flash point: 276.7ºC

Specification:

Items of Analysis	Standard of Analysis	Test Results
Appearance	White to off-white powder	Conforms
Single impurity	≤0.2%	0.03%
Total impurities	≤0.5%	0.14%
Lossing on drying	≤1.0%	0.15%
Residue on ignition	≤0.1%	0.06%
Heavy metals	≤20ppm	Conforms
Assay	99.0%-101.0%	99.5%
Conclusion	Conform to the enterprise standard

Application:

Azelastine hydrochloride is a second generation H1 receptor antagonist.

Package and Storage:

1kg/bottle or bag

25kgs/drum or bag

Market News:Earlier this month, the drugmaker lifted a voluntary EU marketing hold on Zynteglo for beta thalassemia, after a patient death in one of the drugmaker’s other products, LentiGlobin, halted clinical studies. Amino-phenyl-acetic acid (1S,2R,4S)-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester manufacturer.Bluebird determined that death was highly unlikely to have been caused by the delivery virus used in both Zynteglo and LentiGlobin. 1-carbamoyl-3-(2-phenylethyl)urea supplier.Lonza is investing CHF 20 million in GMP laboratories and mid-scale manufacturing assets at its API manufacturing center in Nansha, China. The investment will allow Lonza to provide a smoother transition from small-scale to large-scale manufacturing for customers. 1H-Pyrrole, 1-butyl-2,4-diethyl-3-propyl- producer.

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