Atovaquone Cas:95233-18-4

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Product Description:

Product Name: Atovaquone CAS NO: 95233-18-4

 

Synonyms:

2-Propanol,1-[2-(4-methyl-1,3-dioxolan-2-yl)ethoxy];

2-[trans-4-(4”-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone;

trans-2-[2-(2-hydroxypropoxy)-ethyl]-4-methyl-1,3-dioxolane;

 

Chemical & Physical Properties:

Appearance: Yellow to orange crystalline solid

Assay :≥99.00%

Density: 1.349g/cm3

Boiling Point: 542.2℃ at 760 mmHg

Melting Point: 216-219℃

Flash Point: 281.7±30.1℃

Refractive Index: 1.653

Vapor Pressure: 0.0±1.5 mmHg at 25℃

Storage Condition: -20℃ Freezer

 

Safety Information:

HS Code: 2942000000

WGK Germany: 3

Hazard Code: N

Risk Statements: R50/53

Safety Statements: S60-61

 

Atovaquone (alternative spelling: atavaquone) is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. It is manufactured in the US in the liquid form, or oral suspension, under the brand name Mepron.

Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.Target: AntiparasiticAtovaquone (atavaquone) is a chemical compound that belongs to the class of naphthalenes. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket. Atovaquone is a unique naphthoquinone with broad-spectrum antiprotozoal activity. It is effective for the treatment and prevention of Pneumocystis carinii pneumonia (PCP), it is effective in combination with proguanil for the treatment and prevention of malaria, and it is effective in combination with azithromycin for the treatment of babesiosis .

 

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