Articaine Hydrochloride Cas:23964-57-0

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Articaine Hydrochloride

Product Description:

Product Name: Articaine hydrochloride CAS NO: 23964-57-0

 

Synonyms:

methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate,hydrochloride;

Articaine HCl;

methyl 4-methyl-3-(2-(propylamino)propanamido)thiophene-2-carboxylate hydrochloride;

 

Chemical & Physical Properties:

Appearance: White crystalline powder

Assay :≥99.00%

Density: 1.178 g/cm3

Boiling Point: 440.6℃ at 760 mmHg

Flash Point: 220.3℃

Vapor Pressure: 5.79E-08mmHg at 25℃

 

Safety Information:

HS Code: 2934999090

Hazard Code: Xi

Risk Statements: R36/37/38

Safety Statement: S26

WGK Germany: 3

 

Articaine Hydrochloride is a dental local anesthetic.Target: OthersArticaine Hydrochloride is a dental local anesthetic. Articaine: VAS (Visual Analogue Scale) scores (from 0 to 10 cm) by patients 4 to < 13 years of age are 0.5 for simple procedures and 1.1 for complex procedures, and average investigator scores are 0.4 and 0.6 for simple and complex procedures, respectively. No serious adverse events related to the articaine occurres, the only adverse event considered related to articaine is accidental lip injury in one patient. Articaine results in success rate of 64.5% in electronic pulp testing in healthy adult volunteers injected with 4% articaine. Articaine infiltration produces significantly more episodes of no response to maximum stimulation in first molars than lidocaine. Mandibular buccal infiltration is more effective with 4% articaine with epinephrine compared to 2% lidocaine with epinephrine. Articaine formulation results in successful pulpal anesthesia ranged from 75 to 92 percent and onset of pulpal anesthesia ranged from 4.2 to 4.7 minutes in healthy volunteer. For articaine, 4 percent (two of 56) of the subjects reported swelling and no subjects reported bruising. Ninety-eight percent (59 of 60) of the subjects had lip numbness with the articaine solution.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.



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