Artemisinin

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Synonyms:
(+)-artemisinin
ARTEMISINE
QHS
qinghosu
qinghausu
ARTEANNUIN
Artemisinin
QINGHAOSU
ARTEANUIN
Quinghaosu
[3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one
QINGHAOSA
artemisinine
qinghausau
 
Molecular Formula: C15H22O5
Molecular Weight: 282.33200
 
 
Appearance and properties: crystalline solid
Density: 1.24 g/cm3
Boiling point: 389.9ºC at 760 mmHg
Melting point: 156-157ºC
Flash point: 172ºC
 
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air.
Storage conditions: ventilated, low temperature and dry
Applications: Artemisinin is an antimalarial drug isolated from the aerial part of the Artemisia annua L. plant.

Items of Analysis Standard of Analysis Test Results
Appearance White to off-white crystalline powder Conform
Related Substances Artemisitene ≤0.15% 0.07%
9-epimer of artemisinin ≤0.3% ND
Any individual impurity ≤0.15% 0.10%
Total impurities ≤1.0% 0.75%
Loss on drying ≤0.5% 0.25%
Residue on ignition ≤0.1% 0.06%
Lead ≤2 ppm Conform
Arsenic ≤1 ppm Conform
Mercury ≤0.1 ppm Conform
Cadmium ≤0.1ppm Conform
Aerobic bacteria count ≤1000 cfu/g Conform
Yeast& Mold ≤100 cfu/g Conform
Escherichia coli Negative Conform
Pseudomonas aeruginosa Negative Conform
Staphylococcus aureus Negative Conform
Assay(HPLC) 98.0-102.0% 99.35%
Conclusion Conforms to Factory Standard
 

Artemisinin


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