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Product Description:
Product Name: Abemaciclib CAS NO: 1231929-97-7
Synonyms:
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;
2-Pyrimidinamine,N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl];
LY2835219;
Chemical & Physical Properties:
Appearance: Solid
Assay :≥99.00%
Boiling Point: 689.3±65.0℃(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
Pka: 7.69±0.10(Predicted)
Flash Point: 370.7±34.3℃
Vapour Pressure: 0.0±2.2 mmHg at 25℃
Index of Refraction: 1.656
Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.
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