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Product Description:
Product Name: Ertugliflozin L-pyroglutamic acid CAS NO: 1210344-83-4
Synonyms:
ertugliflozin-L-pyroglutamic acid;
(1S,2S,3S,4R,55)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-hydroxymethyl-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol pyroglutamic acid;
cocrystalof(1S,2S,3S,4R,5S)-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-hydroxymethyl-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol and L-pyroglutamic acid;
Chemical & Physical Properties:
Appearance: Solid powder
Assay :≥99.0%
Melting Point: 142.5℃
Ertugliflozin (PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2].
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