GW-870086 Cas:827319-43-7

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Product Description:

Product Name: GW-870086 CAS NO: 827319-43-7

 

Synonyms:

cyanomethyl(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2,2,3,3-tetramethylcyclopropanecarbonyl)oxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylate;

UNII-O891A2A3ZU;

 

Chemical & Physical Properties:

Appearance: Solid

Assay :≥98.0%

Storage: -20℃ for 3 years in powder form;-80℃ for 2 years in solvent.

 

GW-870086 is a novel and potent glucocorticoid receptor agonist that has anti-inflammatory properties, and thus can be potentially usef for the treatment of asthma and atopic dermatitis.. It acts as a glucocorticoid receptor agonist with a pIC50 of 10.1 in A549 cells expressing NF-κB.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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