6-phenylmethoxy-7H-purin-2-amine Cas:19916-73-5

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Product Description:

Product Name: 6-phenylmethoxy-7H-purin-2-amine CAS NO: 19916-73-5

 

Synonyms:

O-6-Benzylguanine;

2-Amino-6-(benzyloxy)purine;

2-amino-6-(phenylmethoxy)-9H-purine;

 

Chemical & Physical Properties:

Appearance: Light yellow solid

Assay :≥98%

Density: 1.431 g/cm3

Boiling Point: 621.4℃at 760 mmHg

Melting Point: 193℃

Flash Point: 329.6℃

Refractive Index: 1.743

Vapor Pressure: 2.3E-15mmHg at 25℃

Storage Temp.-20℃Freezer

Solubility: methanol: 20 mg/Ml

 

Safety Information:

Signal Word: Warning

Symbol: GHS07

Safety Statements: S26-S36

HS Code: 2933990090

WGK Germany: 3

Risk Statements: R36/37/38

Hazard Code: Xi

Hazard Declaration: H315; H319; H335

Caution Statement: P261; P305 + P351 + P338

 

O6-Benzylguanine (O6-BG) is a synthetic derivative of guanine. It is an antineoplastic agent. It exerts its effect by acting as an inhibitor of the enzyme O6-alkylguanine-DNA alkyltransferase which leads to interruption of DNA repair and increases the potency of other chemotherapeutic agents that damage DNA, such as temozolomide.

O6-BG is also used as a biochemical tool in the study of DNA repair mechanisms.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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