6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Cas:179688-29-0

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Product Description:

Product Name: 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone CAS NO: 179688-29-0

 

Synonyms:

Erlotinib Intermediate V;

6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one;

6,7-di(2”-methoxyethoxy)quinazolin-4(3H)-one;

 

Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%

Density: 1.26 g/cm3

Boiling Point: 467.8℃ at 760 mmHg

Melting Point: 185-189℃

Flash Point: 236.7℃

Refractive Index: 1.552

Vapor Pressure: 6.3E-09mmHg at 25℃

Storage temp.: -20℃ Freezer

Solubility: DMSO: ≥10mg/mL

 

Safety Information:

HS Code: 2933990090

Signal Word: Warning

WGK Germany: 3

Precautionary Statements: P261-P305+P351+P338       

Hazard Statements: H315-H319-H335

 

An intermediate in the synthesis of Erlotinib (E625000). CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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