5-Chloro-2,4-Difluoroaniline

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Chemical Name:    5-Chloro-2,4-Difluoroaniline
CAS.NO: 348-65-2
Synonyms:5-Chlor-2,4-difluor-anilin;
5-Chloro-2,4-difluoroaniline;
5-chloro-2,4-difluoro-aniline;
1-Amino-5-chloro-2,4-difluorobenzene;
5-chloro-2,4-difluorophenylamine;
Molecular Formula:C6H4ClF2N
Molecular Weight: 163.55200
 
Physical and Chemical Properties:
Density: 1.459 g/cm3
Melting point: /
Boiling point: 218.7ºC at 760 mmHg
Flash point:86.1ºC
Index of Refraction:1.543
 
Specification:
Appearance: Light Yellow powder
Purity:≥98.0%
 
Packing:25kg/drum
Storage:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Application:   used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib which is an impurity of the tyrosine kinase inhibitor Gefitinib.

5-Chloro-2,4-Difluoroaniline


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